SAN FRANCISCO, CA – July 5, 2025 – Brightseed, a pioneer in AI-driven bioscience, today announced the official launch of Bio Gut Core™, a groundbreaking digestive health ingredient poised to redefine the functional food and supplement market. Leveraging its proprietary Forager® AI platform, Brightseed has unlocked two novel bioactives, N-trans caffeoyltyramine (NCT) and N-trans feruloyltyramine (NFT), forming the core of this innovative solution.
Clinically Proven for Gut Barrier Strength
What truly differentiates Bio Gut Core is its proven effectiveness. A comprehensive clinical trial confirmed that NCT and NFT notably enhance the gut’s protective barrier. This vital barrier is key for optimal nutrient absorption and keeping unwanted elements out of your bloodstream. Participants in the study reported a clear decrease in typical digestive complaints such as bloating and abdominal pain, with some experiencing relief in as little as seven days and significant positive changes within three weeks of use.
“Not only are we introducing a novel, nature-derived ingredient to the $51 billion digestive market, with Bio Gut Core we’re delivering a next-level solution to provide relief for the tens of millions of Americans affected by debilitating digestive health conditions,” said Lee Chae, PhD, co-founder and CEO, Brightseed. “This gut health clinical data further validates the ability of Brightseed’s AI-driven discovery to meaningfully improve human health and quality of life. We have big plans from here.”
Targeting the Root of Digestive Discomfort
Unlike many existing digestive health solutions that primarily focus on probiotics or general fiber, Bio Gut Core directly targets the integrity of the gut barrier. A compromised gut barrier, often referred to as “leaky gut,” is linked to issues such as dysbiosis, inflammation, and poor nutrient absorption, contributing to symptoms like bloating, gas, diarrhea, and constipation. By activating HNF4⍺, a transcription factor vital for gut barrier function, NCT and NFT in Bio Gut Core work to fortify this critical defense, promoting a thriving environment for the gut microbiome.
Low Dose, High Impact, Versatile Application
Bio Gut Core offers a potent solution in a remarkably low dose (120mg), making it highly versatile for integration into a wide range of products. This proprietary blend of high-purity NCT and NFT, produced via precision fermentation, can be easily formulated into capsules, tablets, soft gels, ready-to-mix powders, and even ready-to-drink beverages. This ease of application opens doors for manufacturers to create next-generation functional foods and supplements that deliver tangible gut health benefits without requiring unfeasibly large doses or causing common digestive discomforts often associated with other prebiotics.
Brightseed continues to push the boundaries of natural ingredient discovery through its AI-powered Forager platform, demonstrating a commitment to improving human health through nature-derived bioactives. Bio Gut Core is now available for companies seeking to elevate their digestive health product offerings with a scientifically validated, high-impact ingredient.